PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

Pulmonary hypertension (PH) is a progressive and often fatal disorder whose pathogenesis involves pulmonary artery smooth muscle cell (PASMC) proliferation. Although modern PH therapies have significantly improved survival, continued progress rests on the discovery of novel therapies and molecular t...

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Detalles Bibliográficos
Autores principales: Green, David E., Murphy, Tamara C., Kang, Bum-Yong, Searles, Charles D., Hart, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514882/
https://www.ncbi.nlm.nih.gov/pubmed/26208095
http://dx.doi.org/10.1371/journal.pone.0133391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514882/
https://www.ncbi.nlm.nih.gov/pubmed/26208095
http://dx.doi.org/10.1371/journal.pone.0133391

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