Acetate: friend or foe? Efficient production of a sweet protein in Escherichia coli BL21 using acetate as a carbon source

BACKGROUND: Escherichia coli is, to date, the most used microorganism for the production of recombinant proteins and biotechnologically relevant metabolites. High density cell cultures allow efficient biomass and protein yields. However, their main limitation is the accumulation of acetate as a by-p...

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Detalles Bibliográficos
Autores principales: Leone, Serena, Sannino, Filomena, Tutino, Maria Luisa, Parrilli, Ermenegilda, Picone, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514960/
https://www.ncbi.nlm.nih.gov/pubmed/26208726
http://dx.doi.org/10.1186/s12934-015-0299-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514960/
https://www.ncbi.nlm.nih.gov/pubmed/26208726
http://dx.doi.org/10.1186/s12934-015-0299-0

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