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The Wilms’ tumour suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A(2) receptor gene in megakaryocytes
In humans, the TPα and TPβ isoforms of the thromboxane A(2) receptor are transcriptionally regulated by distinct promoters, designated Prm1 and Prm3. Previous investigations identified two upstream repressor regions (URR) 1 and URR2 within Prm1. Herein, it was sought to characterize Prm1, identifyin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515072/ https://www.ncbi.nlm.nih.gov/pubmed/19067769 http://dx.doi.org/10.1111/j.1582-4934.2008.00599.x |