Cargando…

The Wilms’ tumour suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A(2) receptor gene in megakaryocytes

In humans, the TPα and TPβ isoforms of the thromboxane A(2) receptor are transcriptionally regulated by distinct promoters, designated Prm1 and Prm3. Previous investigations identified two upstream repressor regions (URR) 1 and URR2 within Prm1. Herein, it was sought to characterize Prm1, identifyin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gannon, AnneMarie M, Kinsella, B Therese
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515072/ https://www.ncbi.nlm.nih.gov/pubmed/19067769 http://dx.doi.org/10.1111/j.1582-4934.2008.00599.x

Ejemplares similares

Implications of the Wilms’ Tumor Suppressor Wt1 in Cardiomyocyte Differentiation
por: Wagner, Nicole, et al.
Publicado: (2021)

PPARβ activation inhibits melanoma cell proliferation involving repression of the Wilms’ tumour suppressor WT1
por: Michiels, Jean-François, et al.
Publicado: (2010)

Wilms’ Tumour gene 1 (WT1) as an immunotherapeutic target
por: Coosemans, A.
Publicado: (2011)

Every Beat You Take—The Wilms′ Tumor Suppressor WT1 and the Heart
por: Wagner, Nicole, et al.
Publicado: (2021)

Diagnostic utility of Wilms’ tumour-1 protein (WT-1) immunostaining in paediatric renal tumours
por: Goyal, Surbhi, et al.
Publicado: (2016)

Wilms’ tumor suppressor gene (WT1) suppresses apoptosis by transcriptionally downregulating BAX expression in immature rat granulosa cells
por: Park, Minji, et al.
Publicado: (2014)

Wilms’ tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway
por: Wang, Xi, et al.
Publicado: (2013)

The Wilms' Tumor Suppressor Protein WT1 Is Processed by the Serine Protease HtrA2/Omi
por: Hartkamp, Jörg, et al.
Publicado: (2010)

The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
por: Legge, Danny, et al.
Publicado: (2021)

A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation
por: Kaneko, Y, et al.
Publicado: (2015)

Long-term kidney function in children with Wilms tumour and constitutional WT1 pathogenic variant
por: Falcone, Maria Pia, et al.
Publicado: (2021)

The Wilms’ tumor (WT1) gene: Methods and protocols
por: Agrawal, Suraksha
Publicado: (2018)

Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus
por: Munari, Leonardo, et al.
Publicado: (2023)

Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2
por: Rapley, E A, et al.
Publicado: (2000)

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
por: Berry, Rachel L., et al.
Publicado: (2015)

The tumor suppressor WT1 drives progenitor cell progression and epithelialization to prevent Wilms tumorigenesis in human kidney organoids
por: Waehle, Verena, et al.
Publicado: (2021)

Deletion of the Wilms’ Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development
por: Díaz del Moral, Sandra, et al.
Publicado: (2021)

Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, wt1, Are Required for Normal Pronephros Development of Xenopus Embryos
por: Shiraki, Taisei, et al.
Publicado: (2022)

Wilms’ Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses
por: Uttenthal, Benjamin, et al.
Publicado: (2014)

Wilms Tumor-1 (WT1) rs16754 Polymorphism
por: Sookaromdee, Pathum, et al.
Publicado: (2019)

Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.
por: Cowell, J. K., et al.
Publicado: (1993)

Wilms' Tumour
por: Pearson, D.
Publicado: (1976)

Prostacyclin and thromboxane in benign and malignant breast tumours.
por: Laekeman, G. M., et al.
Publicado: (1986)

The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells
por: Han, Youqi, et al.
Publicado: (2007)

Circulating microRNA profiles in Wilms tumour (WT): A systematic review and meta-analysis of diagnostic test accuracy
por: Benlhachemi, Sara, et al.
Publicado: (2023)

The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells
por: Ajore, Ram, et al.
Publicado: (2010)

Palmitoylation of the TPβ isoform of the human thromboxane A(2) receptor.: Modulation of G protein: Effector coupling and modes of receptor internalization
por: Reid, Helen M., et al.
Publicado: (2007)

KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway
por: Sousa, Luis, et al.
Publicado: (2020)

Chemotherapy and terminal skeletal muscle differentiation in WT1‐mutant Wilms tumors
por: Royer‐Pokora, Brigitte, et al.
Publicado: (2018)

NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension
por: Mulvaney, Eamon P., et al.
Publicado: (2020)

Wilms' tumour and parental age: a report from the National Wilms' Tumour Study.
por: Olson, J. M., et al.
Publicado: (1993)

TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels
por: Makki, Mohammad Shahidul, et al.
Publicado: (2008)

Studies of Wilms’ Tumor (WT1) Gene Expression in Adult Acute Leukemias in Singapore
por: Lim, Che Kang, et al.
Publicado: (2007)

Nephron, Wilms’ tumor-1 (WT1), and synaptopodin expression in developing podocytes of mice
por: Kato, Takashi, et al.
Publicado: (2017)

The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis
por: Nathan, Abinaya, et al.
Publicado: (2017)

Nlz1/Znf703 acts as a repressor of transcription
por: Nakamura, Mako, et al.
Publicado: (2008)

The stem and roots of Wilms' tumours
por: Hohenstein, Peter
Publicado: (2013)

Antenatally Diagnosed Wilms’ Tumour
por: Sarin, YK, et al.
Publicado: (2014)

Molecular Biology of Wilm's Tumour
por: Shaw, A. P. W., et al.
Publicado: (1988)

Wilms’ tumour and chemotherapeutic access
por: Yasri, Sora, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_g9jf8gd77tcsv3jqfgihhu06ec