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Evidence for glycosylation as a regulator of the pigmentary system: key roles of sialyl(α2-6)gal/GalNAc-terminated glycans in melanin synthesis and transfer

The major regulators of melanogenesis are glycoproteins, however no role for glycosylation in the pathway has yet been described. We stained skin biopsies and melanocyte-keratinocyte co-cultures with a panel of 20 lectins as oligosaccharide markers. Notably, the Elderberry Bark Lectin (EBL/SNA) stai...

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Detalles Bibliográficos
Autores principales: Diwakar, Ganesh, Klump, Vincent, Lazova, Rossitza, Pawelek, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515250/
https://www.ncbi.nlm.nih.gov/pubmed/26194059
http://dx.doi.org/10.1007/s10719-015-9605-7