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Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation

Both oxidative stress and mast cell (MC) degranulation participate in the process of small intestinal ischemia reperfusion (IIR) injury, and oxidative stress induces MC degranulation. Propofol, an anesthetic with antioxidant property, can attenuate IIR injury. We postulated that propofol can protect...

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Detalles Bibliográficos
Autores principales: Gan, Xiaoliang, Xing, Dandan, Su, Guangjie, Li, Shun, Luo, Chenfang, Irwin, Michael G., Xia, Zhengyuan, Li, Haobo, Hei, Ziqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515292/
https://www.ncbi.nlm.nih.gov/pubmed/26246867
http://dx.doi.org/10.1155/2015/167014