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The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity

Secretory Leukocyte Protease Inhibitor (SLPI) is a serine protease inhibitor produced by epithelial and myeloid cells with anti-inflammatory properties. Research has shown that SLPI exerts its anti-inflammatory activity by directly binding to NF-κB DNA binding sites and, in so doing, prevents bindin...

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Detalles Bibliográficos
Autores principales: McGarry, Niamh, Greene, Catherine M., McElvaney, Noel G., Weldon, Sinéad, Taggart, Clifford C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515294/
https://www.ncbi.nlm.nih.gov/pubmed/26247039
http://dx.doi.org/10.1155/2015/507315