Cargando…

Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation

BACKGROUND: Many cancer cells exhibit reduced mitochondrial respiration as part of metabolic reprogramming to support tumor growth. Mitochondrial localization of several protein tyrosine kinases is linked to this characteristic metabolic shift in solid tumors, but remains largely unknown in blood ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Vahedi, Shahrooz, Chueh, Fu-Yu, Chandran, Bala, Yu, Chao-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515320/
https://www.ncbi.nlm.nih.gov/pubmed/26210498
http://dx.doi.org/10.1186/s12885-015-1520-6