C-Jun N-terminal kinases are required for oncolytic adenovirus-mediated autophagy

Oncolytic adenoviruses, such as Delta-24-RGD, are replication-competent viruses that are genetically engineered to induce selective cancer cell lysis. In cancer cells, Delta-24-RGD induces massive autophagy, which is required for efficient cell lysis and adenoviral spread. Understanding the cellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, SR, Piya, S, Lu, Z, Xia, Y, Alonso, MM, White, EJ, Wei, J, Gomez-Manzano, C, Jiang, H, Fueyo, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515398/
https://www.ncbi.nlm.nih.gov/pubmed/25619840
http://dx.doi.org/10.1038/onc.2014.452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515398/
https://www.ncbi.nlm.nih.gov/pubmed/25619840
http://dx.doi.org/10.1038/onc.2014.452

Ejemplares similares