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Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before drug treatment

The epidemiology of Mycobacterium tuberculosis (Mtb) and M. africanum (Maf) suggest differences in their virulence, but the host immune profile to better understand the pathogenesis of tuberculosis (TB) have not been studied. We compared the transcriptomic and metabolic profiles between Mtb and Maf-...

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Detalles Bibliográficos
Autores principales: Tientcheu, Leopold D., Maertzdorf, Jeroen, Weiner, January, Adetifa, Ifedayo M., Mollenkopf, Hans-Joachim, Sutherland, Jayne S., Donkor, Simon, Kampmann, Beate, Kaufmann, Stefan H. E., Dockrell, Hazel M., Ota, Martin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515549/
https://www.ncbi.nlm.nih.gov/pubmed/26043170
http://dx.doi.org/10.1038/gene.2015.21