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In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex

A wide variety of prokaryotes possess DNA modifications consisting of sequence-specific phosphorothioates (PT) inserted by members of a five-gene cluster. Recent genome mapping studies revealed two unusual features of PT modifications: short consensus sequences and partial modification of a specific...

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Detalles Bibliográficos
Autores principales: Cao, Bo, Zheng, Xiaoqing, Cheng, Qiuxiang, Yao, Fen, Zheng, Tao, Ramesh Babu, I., Zhou, Huchen, Dedon, Peter, You, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515589/
https://www.ncbi.nlm.nih.gov/pubmed/26213215
http://dx.doi.org/10.1038/srep12513