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Identification of the Scopularide Biosynthetic Gene Cluster in Scopulariopsis brevicaulis

Scopularide A is a promising potent anticancer lipopeptide isolated from a marine derived Scopulariopsis brevicaulis strain. The compound consists of a reduced carbon chain (3-hydroxy-methyldecanoyl) attached to five amino acids (glycine, l-valine, d-leucine, l-alanine, and l-phenylalanine). Using t...

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Detalles Bibliográficos
Autores principales: Lukassen, Mie Bech, Saei, Wagma, Sondergaard, Teis Esben, Tamminen, Anu, Kumar, Abhishek, Kempken, Frank, Wiebe, Marilyn G., Sørensen, Jens Laurids
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515620/
https://www.ncbi.nlm.nih.gov/pubmed/26184239
http://dx.doi.org/10.3390/md13074331