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Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids

The role of autophagy in cell death is still controversial and a lot of debate has concerned the transition from its pro-survival to its pro-death roles. The similar structure of the triterpenoids Betulinic (BA) and Oleanolic (OA) acids allowed us to prove that this transition involves parallel dama...

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Detalles Bibliográficos
Autores principales: Martins, Waleska K., Costa, Érico T., Cruz, Mário C., Stolf, Beatriz S., Miotto, Ronei, Cordeiro, Rodrigo M., Baptista, Maurício S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515638/
https://www.ncbi.nlm.nih.gov/pubmed/26213355
http://dx.doi.org/10.1038/srep12425