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Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids
The role of autophagy in cell death is still controversial and a lot of debate has concerned the transition from its pro-survival to its pro-death roles. The similar structure of the triterpenoids Betulinic (BA) and Oleanolic (OA) acids allowed us to prove that this transition involves parallel dama...
Autores principales: | Martins, Waleska K., Costa, Érico T., Cruz, Mário C., Stolf, Beatriz S., Miotto, Ronei, Cordeiro, Rodrigo M., Baptista, Maurício S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515638/ https://www.ncbi.nlm.nih.gov/pubmed/26213355 http://dx.doi.org/10.1038/srep12425 |
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