Cargando…

The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

Among the identified thousands of circular RNAs (circRNA) in humans and animals, Cdr1as (also known as CiRS-7) was recently demonstrated to act as a powerful miR-7 sponge/inhibitor in developing midbrain of zebrafish, suggesting a novel mechanism for regulating microRNA functions. MiR-7 is abundantl...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Huanyu, Guo, Sen, Li, Wei, Yu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515639/
https://www.ncbi.nlm.nih.gov/pubmed/26211738
http://dx.doi.org/10.1038/srep12453