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The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells
Among the identified thousands of circular RNAs (circRNA) in humans and animals, Cdr1as (also known as CiRS-7) was recently demonstrated to act as a powerful miR-7 sponge/inhibitor in developing midbrain of zebrafish, suggesting a novel mechanism for regulating microRNA functions. MiR-7 is abundantl...
Autores principales: | Xu, Huanyu, Guo, Sen, Li, Wei, Yu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515639/ https://www.ncbi.nlm.nih.gov/pubmed/26211738 http://dx.doi.org/10.1038/srep12453 |
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