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Intrinsically disordered proteins drive membrane curvature

Assembly of highly curved membrane structures is essential to cellular physiology. The prevailing view has been that proteins with curvature-promoting structural motifs, such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending membranes. Here we report that in...

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Detalles Bibliográficos
Autores principales: Busch, David J., Houser, Justin R., Hayden, Carl C., Sherman, Michael B., Lafer, Eileen M., Stachowiak, Jeanne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515776/
https://www.ncbi.nlm.nih.gov/pubmed/26204806
http://dx.doi.org/10.1038/ncomms8875