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Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity

Cancer is widely recognized as a genetic disease in which somatic mutations are sequentially accumulated to drive tumor progression. Although genomic landscape studies are informative for individual cancer types, a comprehensive comparative study of tumorigenic mutations across cancer types based on...

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Detalles Bibliográficos
Autores principales: Tan, Hua, Bao, Jiguang, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515826/
https://www.ncbi.nlm.nih.gov/pubmed/26212640
http://dx.doi.org/10.1038/srep12566