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Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity
Cancer is widely recognized as a genetic disease in which somatic mutations are sequentially accumulated to drive tumor progression. Although genomic landscape studies are informative for individual cancer types, a comprehensive comparative study of tumorigenic mutations across cancer types based on...
Autores principales: | Tan, Hua, Bao, Jiguang, Zhou, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515826/ https://www.ncbi.nlm.nih.gov/pubmed/26212640 http://dx.doi.org/10.1038/srep12566 |
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