Cargando…

Eculizumab-induced reversal of dialysis-dependent kidney failure from C3 glomerulonephritis

C3 glomerulopathy (C3G) is characterized by C3 deposits with minimal immunoglobulin deposition caused by alternative complement pathway dysregulation. Unfortunately, no therapeutic intervention has consistently improved outcomes for patients with C3G. Eculizumab, a monoclonal antibody to C5, is curr...

Descripción completa

Detalles Bibliográficos
Autores principales: Inman, Melissa, Prater, Ginnie, Fatima, Huma, Wallace, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515899/
https://www.ncbi.nlm.nih.gov/pubmed/26251714
http://dx.doi.org/10.1093/ckj/sfv044