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Impairment of neutrophilic glucocorticoid receptor function in patients treated with steroids for septic shock

BACKGROUND: Glucocorticoid (GC) treatment has variable effect in sepsis. This may be explained by decreased expression or function of the glucocorticoid receptor (GR). The aim of this study was to determine GR expression and binding capacity in patients during and after sepsis. METHODS: In this pros...

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Detalles Bibliográficos
Autores principales: Bergquist, Maria, Lindholm, Catharina, Strinnholm, Morten, Hedenstierna, Göran, Rylander, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516153/
https://www.ncbi.nlm.nih.gov/pubmed/26215823
http://dx.doi.org/10.1186/s40635-015-0059-9