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Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study

BACKGROUND: The blood–brain barrier prevents many drug moieties from reaching the central nervous system. Therefore, glutathione-modulated nanoliposomes have been engineered to enhance the targeting of flucytosine to the brain. METHODS: Glutathione-modulated nanoliposomes were prepared by thin-film...

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Detalles Bibliográficos
Autores principales: Salem, Heba F, Ahmed, Sayed M, Hassaballah, Ashraf E, Omar, Mahmoud M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516201/
https://www.ncbi.nlm.nih.gov/pubmed/26229435
http://dx.doi.org/10.2147/DDDT.S85302