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Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study
BACKGROUND: The blood–brain barrier prevents many drug moieties from reaching the central nervous system. Therefore, glutathione-modulated nanoliposomes have been engineered to enhance the targeting of flucytosine to the brain. METHODS: Glutathione-modulated nanoliposomes were prepared by thin-film...
Autores principales: | Salem, Heba F, Ahmed, Sayed M, Hassaballah, Ashraf E, Omar, Mahmoud M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516201/ https://www.ncbi.nlm.nih.gov/pubmed/26229435 http://dx.doi.org/10.2147/DDDT.S85302 |
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