TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

The ten-eleven-translocation 5-methylcytosine dioxygenase (TET) family of enzymes catalyzes the conversion of 5-methylcytosine (5-mC) to 5-hydroxyme-thylcytosine (5-hmC), a modified cytosine base that facilitates gene expression. Cells respond to hypoxia by inducing a transcriptional program regulat...

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Detalles Bibliográficos
Autores principales: Mariani, Christopher J., Vasanthakumar, Aparna, Madzo, Jozef, Yesilkanal, Ali, Bhagat, Tushar, Yu, Yiting, Bhattacharyya, Sanchari, Wenger, Roland H., Cohn, Susan L., Nanduri, Jayasri, Verma, Amit, Prabhakar, Nanduri R., Godley, Lucy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516227/
https://www.ncbi.nlm.nih.gov/pubmed/24835990
http://dx.doi.org/10.1016/j.celrep.2014.04.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516227/
https://www.ncbi.nlm.nih.gov/pubmed/24835990
http://dx.doi.org/10.1016/j.celrep.2014.04.040

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