Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes

Betaine-homocysteine S-methyltransferase (BHMT) and BHMT2 convert homocysteine to methionine using betaine and S-methylmethionine, respectively, as methyl donor substrates. Increased levels of homocysteine in blood are associated with cardiovascular disease. Given their role in human health and nutr...

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Detalles Bibliográficos
Autores principales: Ganu, Radhika S., Ishida, Yasuko, Koutmos, Markos, Kolokotronis, Sergios-Orestis, Roca, Alfred L., Garrow, Timothy A., Schook, Lawrence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516251/
https://www.ncbi.nlm.nih.gov/pubmed/26213999
http://dx.doi.org/10.1371/journal.pone.0134084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516251/
https://www.ncbi.nlm.nih.gov/pubmed/26213999
http://dx.doi.org/10.1371/journal.pone.0134084

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