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Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes

Betaine-homocysteine S-methyltransferase (BHMT) and BHMT2 convert homocysteine to methionine using betaine and S-methylmethionine, respectively, as methyl donor substrates. Increased levels of homocysteine in blood are associated with cardiovascular disease. Given their role in human health and nutr...

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Detalles Bibliográficos
Autores principales:	Ganu, Radhika S., Ishida, Yasuko, Koutmos, Markos, Kolokotronis, Sergios-Orestis, Roca, Alfred L., Garrow, Timothy A., Schook, Lawrence B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516251/ https://www.ncbi.nlm.nih.gov/pubmed/26213999 http://dx.doi.org/10.1371/journal.pone.0134084

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