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Pneumococal Surface Protein A (PspA) Regulates Programmed Death Ligand 1 Expression on Dendritic Cells in a Toll-Like Receptor 2 and Calcium Dependent Manner

Pneumonia leads to high mortality in children under the age of five years worldwide, resulting in close to 20 percent of all deaths in this age group. Therefore, investigations into host-pathogen interactions during Streptococcus pneumoniae infection are key in devising strategies towards the develo...

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Detalles Bibliográficos
Autores principales: Vashishta, Mohit, Khan, Naeem, Mehto, Subhash, Sehgal, Devinder, Natarajan, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516265/
https://www.ncbi.nlm.nih.gov/pubmed/26214513
http://dx.doi.org/10.1371/journal.pone.0133601