Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens

Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom is that natural selection will remove highly lethal pathogens if host death greatly reduces transmission. Vaccines that keep hosts alive but still allow transmission could thus allow very virulent strains to circ...

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Detalles Bibliográficos
Autores principales: Read, Andrew F., Baigent, Susan J., Powers, Claire, Kgosana, Lydia B., Blackwell, Luke, Smith, Lorraine P., Kennedy, David A., Walkden-Brown, Stephen W., Nair, Venugopal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516275/
https://www.ncbi.nlm.nih.gov/pubmed/26214839
http://dx.doi.org/10.1371/journal.pbio.1002198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516275/
https://www.ncbi.nlm.nih.gov/pubmed/26214839
http://dx.doi.org/10.1371/journal.pbio.1002198

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