Anti-Neoplastic Cytotoxicity of Gemcitabine-(C(4)-amide)-[anti-HER2/neu] in Combination with Griseofulvin against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3)

INTRODUCTION: Gemcitabine is a pyrimidine nucleoside analog that becomes triphosphorylated and in this form it competitively inhibits cytidine incorporation into DNA strands. Diphosphorylated gemcitabine irreversibly inhibits ribonucleotide reductase thereby preventing deoxyribonucleotide synthesis....

Descripción completa

Detalles Bibliográficos
Autores principales: Coyne, CP, Jones, Toni, Bear, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516389/
https://www.ncbi.nlm.nih.gov/pubmed/26225219
http://dx.doi.org/10.4172/2161-0444.1000141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516389/
https://www.ncbi.nlm.nih.gov/pubmed/26225219
http://dx.doi.org/10.4172/2161-0444.1000141

Ejemplares similares