How genetic errors in GPCRs affect their function: Possible therapeutic strategies

Activating and inactivating mutations in numerous human G protein-coupled receptors (GPCRs) are associated with a wide range of disease phenotypes. Here we use several class A GPCRs with a particularly large set of identified disease-associated mutations, many of which were biochemically characteriz...

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Detalles Bibliográficos
Autores principales: Stoy, Henriette, Gurevich, Vsevolod V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516391/
https://www.ncbi.nlm.nih.gov/pubmed/26229975
http://dx.doi.org/10.1016/j.gendis.2015.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516391/
https://www.ncbi.nlm.nih.gov/pubmed/26229975
http://dx.doi.org/10.1016/j.gendis.2015.02.005

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