Mechanisms underlying fibronectin-induced up-regulation of P2X(4)R expression in microglia: distinct roles of PI3K–Akt and MEK–ERK signalling pathways

ABSTRACT: MICROGLIA: are resident immune cells in the central nervous system that become activated and produce pro-inflammatory and neurotrophic factors upon activation of various cell-surface receptors. The P2X(4) receptor (P2X(4)R) is a sub-type of the purinergic ion-channel receptors expressed in...

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Detalles Bibliográficos
Autores principales: Tsuda, Makoto, Toyomitsu, Emika, Kometani, Miho, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516482/
https://www.ncbi.nlm.nih.gov/pubmed/19298529
http://dx.doi.org/10.1111/j.1582-4934.2009.00719.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516482/
https://www.ncbi.nlm.nih.gov/pubmed/19298529
http://dx.doi.org/10.1111/j.1582-4934.2009.00719.x

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