Functional characterization and pharmacological rescue of melanocortin-4 receptor mutations identified from obese patients

As the most common monogenic form of human obesity, about 130 naturally occurring melanocortin-4 receptor (MC4R) gene mutations have been identified. In this study, we reported detailed functional characterization of 10 novel human MC4R (hMC4R) mutants including R7C, C84R, S127L, S136F, W174C, A219V...

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Detalles Bibliográficos
Autores principales: Fan, Zhen-Chuan, Tao, Ya-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516484/
https://www.ncbi.nlm.nih.gov/pubmed/19298524
http://dx.doi.org/10.1111/j.1582-4934.2009.00726.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516484/
https://www.ncbi.nlm.nih.gov/pubmed/19298524
http://dx.doi.org/10.1111/j.1582-4934.2009.00726.x

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