Cargando…
Functional characterization and pharmacological rescue of melanocortin-4 receptor mutations identified from obese patients
As the most common monogenic form of human obesity, about 130 naturally occurring melanocortin-4 receptor (MC4R) gene mutations have been identified. In this study, we reported detailed functional characterization of 10 novel human MC4R (hMC4R) mutants including R7C, C84R, S127L, S136F, W174C, A219V...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516484/ https://www.ncbi.nlm.nih.gov/pubmed/19298524 http://dx.doi.org/10.1111/j.1582-4934.2009.00726.x |