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Functionalized self-assembling peptide hydrogel enhance maintenance of hepatocyte activity in vitro

There is a major challenge in maintaining functional hepatocytes in vivo as these cells rapidly lose their metabolic properties in culture. In this work we have developed a bioengineered platform that replaces the use of the collagen I – in the traditional culture sandwich technique – by a defined e...

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Detalles Bibliográficos
Autores principales: Genové, Elsa, Schmitmeier, Stephanie, Sala, Ana, Borrós, Salvador, Bader, Augustinus, Griffith, Linda G, Semino, Carlos E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516494/
https://www.ncbi.nlm.nih.gov/pubmed/19912437
http://dx.doi.org/10.1111/j.1582-4934.2009.00970.x