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Dedifferentiation of human articular chondrocytes is associated with alterations in expression patterns of GDF-5 and its receptors

Human articular chondrocytes are expanded in monolayer culture in order to obtain sufficient cells for matrix-associated cartilage transplantation. During this proliferation process, the cells change their shape as well as their expression profile. These changes resemble those that occur during embr...

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Detalles Bibliográficos
Autores principales: Schlegel, Werner, Albrecht, Christian, Eckl, Peter, Freudenthaler, Harald, Berger, Angelika, Vécsei, Vilmos, Marlovits, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516495/
https://www.ncbi.nlm.nih.gov/pubmed/19874419
http://dx.doi.org/10.1111/j.1582-4934.2009.00953.x