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Epigenetic programming of μ-opioid receptor gene in mouse brain is regulated by MeCP2 and brg1 chromatin remodelling factor

The pharmacological action of morphine as a pain medication is mediated primarily through the μ-opioid receptor (MOR). With few exceptions, MOR is expressed in brain regions where opioid actions take place. The basis for this unique spatial expression of MOR remains undetermined. Recently, we report...

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Detalles Bibliográficos
Autores principales: Hwang, Cheol Kyu, Song, Kyu Young, Kim, Chun Sung, Choi, Hack Sun, Guo, Xiao-Hong, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516510/
https://www.ncbi.nlm.nih.gov/pubmed/19602036
http://dx.doi.org/10.1111/j.1582-4934.2008.00535.x