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AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells
The role of autophagy in cisplatin anticancer action was investigated using human U251 glioma, rat C6 glioma and mouse L929 fibrosarcoma cell lines. A dose- and time-dependent induction of autophagy was observed in tumour cells following cisplatin treatment, as demonstrated by up-regulation of autop...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516513/ https://www.ncbi.nlm.nih.gov/pubmed/20196784 http://dx.doi.org/10.1111/j.1582-4934.2009.00663.x |