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AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

The role of autophagy in cisplatin anticancer action was investigated using human U251 glioma, rat C6 glioma and mouse L929 fibrosarcoma cell lines. A dose- and time-dependent induction of autophagy was observed in tumour cells following cisplatin treatment, as demonstrated by up-regulation of autop...

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Detalles Bibliográficos
Autores principales:	Harhaji-Trajkovic, L, Vilimanovich, U, Kravic-Stevovic, T, Bumbasirevic, V, Trajkovic, V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Cell Death
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516513/ https://www.ncbi.nlm.nih.gov/pubmed/20196784 http://dx.doi.org/10.1111/j.1582-4934.2009.00663.x

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