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Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and β-catenin levels

Endostatin is a well-characterized endogenous inhibitor of angiogenesis that affects cell proliferation and migration by inhibiting integrin and Wnt-mediated signalling pathways. Here, we show that endothelial cells treated with native and P125A-endostatin activate autophagy. Because autophagy can e...

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Detalles Bibliográficos
Autores principales: Nguyen, Tri Minh Bui, Subramanian, Indira V, Xiao, Xue, Ghosh, Goutam, Nguyen, Phan, Kelekar, Ameeta, Ramakrishnan, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516517/
https://www.ncbi.nlm.nih.gov/pubmed/19298526
http://dx.doi.org/10.1111/j.1582-4934.2009.00722.x