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Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and β-catenin levels
Endostatin is a well-characterized endogenous inhibitor of angiogenesis that affects cell proliferation and migration by inhibiting integrin and Wnt-mediated signalling pathways. Here, we show that endothelial cells treated with native and P125A-endostatin activate autophagy. Because autophagy can e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516517/ https://www.ncbi.nlm.nih.gov/pubmed/19298526 http://dx.doi.org/10.1111/j.1582-4934.2009.00722.x |