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A common hereditary single-nucleotide polymorphism in the gene of FAS and colorectal cancer survival

Apoptosis plays an important role in embryogenesis, autoimmunity and tumourigenesis. Cell surface death receptors such as TNFRSF6 (FAS) confer a major apoptotic effect. A single-nucleotide polymorphism in the FAS promoter gene, −670A/G, modulates apoptotic signalling and has been related to suscepti...

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Detalles Bibliográficos
Autores principales: Hofmann, Guenter, Langsenlehner, Uwe, Langsenlehner, Tanja, Yazdani-Biuki, Babak, Clar, Heimo, Gerger, Armin, Fuerst, Florentine, Samonigg, Hellmut, Krippl, Peter, Renner, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516518/
https://www.ncbi.nlm.nih.gov/pubmed/19298528
http://dx.doi.org/10.1111/j.1582-4934.2009.00720.x