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HER-2 overexpression/amplification in Barrett’s oesophagus predicts early transition from dysplasia to adenocarcinoma: a clinico-pathologic study

Barrett’s oesophagus (BO) is the primary precursor lesion for oesophageal adenocarcinoma (ADC). The natural history of metaplasia-dysplasia-carcinoma sequence remains largely unknown. HER2/neu oncogene results overexpressed/amplified in preneoplastic lesions and in ADC of the oesophagus and it has b...

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Detalles Bibliográficos
Autores principales: Rossi, Elisa, Grisanti, Salvatore, Villanacci, Vincenzo, Casa, Domenico Della, Cengia, Paolo, Missale, Guido, Minelli, Luigi, Buglione, Michela, Cestari, Renzo, Bassotti, Gabrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516530/
https://www.ncbi.nlm.nih.gov/pubmed/19292734
http://dx.doi.org/10.1111/j.1582-4934.2008.00517.x