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Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response
Taxane and vinblastine represent two classes of microtubules-targeted agents for cancer chemotherapy. Although taxol and vinblastine are widely used for cancer treatment, resistance to these agents is frequently encountered in the clinic. An ongoing question has been what mechanisms are involved in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516536/ https://www.ncbi.nlm.nih.gov/pubmed/19674193 http://dx.doi.org/10.1111/j.1582-4934.2009.00873.x |