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A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc

N-methyl-d-aspartate (NMDA) receptors, one of the three main types of ionotropic glutamate receptors (iGluRs), are involved in excitatory synaptic transmission, and their dysfunction is implicated in various neurological disorders. NMDA receptors, heterotetramers typically composed of GluN1 and GluN...

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Detalles Bibliográficos
Autores principales: Sirrieh, Rita E., MacLean, David M., Jayaraman, Vasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516779/
https://www.ncbi.nlm.nih.gov/pubmed/26170175
http://dx.doi.org/10.1085/jgp.201511422