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Proton block of proton-activated TRPV1 current

The TRPV1 cation channel is a polymodal nociceptor that is activated by heat and ligands such as capsaicin and is highly sensitive to changes in extracellular pH. In the body core, where temperature is usually stable and capsaicin is normally absent, H(+) released in response to ischemia, tissue inj...

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Detalles Bibliográficos
Autores principales: Lee, Bo Hyun, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516785/
https://www.ncbi.nlm.nih.gov/pubmed/26170176
http://dx.doi.org/10.1085/jgp.201511386