CCND1–CDK4–mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo

Maintenance of stem cell properties is associated with reduced proliferation. However, in mouse hematopoietic stem cells (HSCs), loss of quiescence results in a wide range of phenotypes, ranging from functional failure to extensive self-renewal. It remains unknown whether the function of human HSCs...

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Detalles Bibliográficos
Autores principales: Mende, Nicole, Kuchen, Erika E., Lesche, Mathias, Grinenko, Tatyana, Kokkaliaris, Konstantinos D., Hanenberg, Helmut, Lindemann, Dirk, Dahl, Andreas, Platz, Alexander, Höfer, Thomas, Calegari, Federico, Waskow, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516798/
https://www.ncbi.nlm.nih.gov/pubmed/26150472
http://dx.doi.org/10.1084/jem.20150308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516798/
https://www.ncbi.nlm.nih.gov/pubmed/26150472
http://dx.doi.org/10.1084/jem.20150308

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