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CCND1–CDK4–mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo
Maintenance of stem cell properties is associated with reduced proliferation. However, in mouse hematopoietic stem cells (HSCs), loss of quiescence results in a wide range of phenotypes, ranging from functional failure to extensive self-renewal. It remains unknown whether the function of human HSCs...
Autores principales: | Mende, Nicole, Kuchen, Erika E., Lesche, Mathias, Grinenko, Tatyana, Kokkaliaris, Konstantinos D., Hanenberg, Helmut, Lindemann, Dirk, Dahl, Andreas, Platz, Alexander, Höfer, Thomas, Calegari, Federico, Waskow, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516798/ https://www.ncbi.nlm.nih.gov/pubmed/26150472 http://dx.doi.org/10.1084/jem.20150308 |
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