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T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi

Generation of T lymphocytes in the thymus is guided by signal transduction from the T cell receptor (TCR), but the underlying mechanism is incompletely understood. Here we have identified a Golgi-associated factor, TRAF3-interacting protein 3 (TRAF3IP3), as a crucial mediator of thymocyte developmen...

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Detalles Bibliográficos
Autores principales: Zou, Qiang, Jin, Jin, Xiao, Yichuan, Hu, Hongbo, Zhou, Xiaofei, Jie, Zuliang, Xie, Xiaoping, Li, James Y.H., Cheng, Xuhong, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516800/
https://www.ncbi.nlm.nih.gov/pubmed/26195727
http://dx.doi.org/10.1084/jem.20150110