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Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder
Phosphorylation events that occur in response to the second messenger cAMP are controlled spatially and temporally by protein kinase A (PKA) interacting with A-kinase anchoring proteins (AKAPs). Recent advances in understanding the structural basis for this interaction have reinforced the hypothesis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516873/ https://www.ncbi.nlm.nih.gov/pubmed/26283967 http://dx.doi.org/10.3389/fphar.2015.00158 |