Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms

The 5-HT(3) receptor is a ligand-gated ion channel, which is expressed in the nervous system. Its antagonists are used clinically for treatment of postoperative- and radiotherapy-induced emesis and irritable bowel syndrome. In order to better understand the structure and function of the 5-HT(3) rece...

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Detalles Bibliográficos
Autores principales: Otvos, Reka A., Krishnamoorthy Iyer, Janaki, van Elk, René, Ulens, Chris, Niessen, Wilfried M. A., Somsen, Govert W., Kini, R. Manjunatha, Smit, August B., Kool, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516916/
https://www.ncbi.nlm.nih.gov/pubmed/26114334
http://dx.doi.org/10.3390/toxins7072336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516916/
https://www.ncbi.nlm.nih.gov/pubmed/26114334
http://dx.doi.org/10.3390/toxins7072336

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