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Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge

Protective immunity against anthrax is inferred from measurement of vaccine antigen-specific neutralizing antibody titers in serum samples. In animal models, in vivo challenges with toxin and/or spores can also be performed. However, neither of these approaches considers toxin-induced damage to spec...

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Detalles Bibliográficos
Autores principales: Devera, T. Scott, Prusator, Dawn K., Joshi, Sunil K., Ballard, Jimmy D., Lang, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516918/
https://www.ncbi.nlm.nih.gov/pubmed/26120785
http://dx.doi.org/10.3390/toxins7072371